Basic Information
ID: ALA2173435
Type: Binding
Description: Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 mins
Organism: Homo sapiens
Cell type: HT-29
Activity Charts
Bioactivity
Activity Types for Assay ALA2173435
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 408.38 | 1.62 | 1.62 |
| 380.47 | 0.75 | 0.75 |
| 384.40 | 2.83 | 2.83 |
| 398.43 | 3.08 | 3.08 |
| 384.40 | 2.69 | 2.69 |
| 382.39 | 2.44 | 2.44 |
| 386.37 | 1.68 | 1.68 |
| 370.38 | 2.44 | 2.44 |
| 356.35 | 2.05 | 2.05 |
| 370.38 | 2.36 | 2.36 |
| 386.37 | 2.06 | 2.06 |
| 380.47 | 0.83 | 0.83 |
| 366.44 | 0.44 | 0.44 |
| 394.50 | 1.14 | 1.14 |
| 497.50 | 2.00 | 2.00 |
| 436.44 | 2.39 | 2.39 |
| 422.41 | 2.08 | 2.08 |
| 422.41 | 2.08 | 2.08 |
| 448.45 | 3.36 | 3.36 |
| 475.47 | 2.71 | 2.71 |
| 489.50 | 3.05 | 3.05 |
| 511.53 | 2.26 | 2.26 |
| 525.55 | 2.60 | 2.60 |
| 410.44 | 3.22 | 3.22 |
| 398.43 | 3.08 | 3.08 |
| 485.47 | 4.00 | 4.00 |
| 484.48 | 3.53 | 3.53 |
| 434.42 | 3.05 | 3.05 |
| 443.43 | 3.22 | 3.22 |
| 443.43 | 3.22 | 3.22 |
| 443.43 | 3.22 | 3.22 |
| 496.51 | 2.75 | 2.75 |
| 496.51 | 2.75 | 2.75 |
| 496.51 | 2.75 | 2.75 |
| 419.41 | 2.74 | 2.74 |
| 419.41 | 2.74 | 2.74 |
| 419.41 | 2.74 | 2.74 |
| 461.44 | 2.45 | 2.45 |
| 435.41 | 2.45 | 2.45 |
| 422.41 | 2.06 | 2.06 |
| 407.40 | 2.68 | 2.68 |
| 418.42 | 3.35 | 3.35 |
| 436.41 | 3.49 | 3.49 |
| 486.42 | 4.37 | 4.37 |
| 452.86 | 4.00 | 4.00 |
| 452.86 | 4.00 | 4.00 |
| 452.86 | 4.00 | 4.00 |
| 494.52 | 5.02 | 5.02 |
| 485.47 | 4.00 | 4.00 |
| 408.38 | 1.67 | 1.67 |
| 422.41 | 2.06 | 2.06 |