Basic Information
ID: ALA2173473
Type: Functional
Description: Agonist activity at SHP1 in human PLC5 cells assessed as inhibition of IL6-induced STAT3 phosphorylation at 10 uM incubated for 24 hrs prior to IL6-induction measured after 30 mins by sandwich ELISA
Format: BAO_0000219
Organism: Homo sapiens
Cell type: PLC5
Target: Protein-tyrosine phosphatase 1C(ALA3166)
Document: ALA2169881
Agonist activity at SHP1 in human PLC5 cells assessed as inhibition of IL6-induced STAT3 phosphorylation at 10 uM incubated for 24 hrs prior to IL6-induction measured after 30 mins by sandwich ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2173473
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.23 | 4.63 | 4.63 |
| 289.34 | 3.87 | 3.87 |
| 404.47 | 6.02 | 6.02 |