Basic Information
ID: ALA2173490
Type: Functional
Description: Antagonist at human recombinant GABA-A alpha1beta2gamma2L receptor expressed in Xenopus laevis oocytes assessed as blockade of diazepam-induced potentiation of GABA-induced chloride current at 10 uM incubated 60 seconds before addition of GABA measured after 30 seconds at holding potential -70 mV by two-microelectrode voltage clamp technique
Organism: Homo sapiens
Cell type: Oocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA2173490
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 394.36 | 3.45 | 3.45 |
| 365.82 | 4.05 | 4.05 |
| 345.40 | 3.71 | 3.71 |
| 367.36 | 3.68 | 3.68 |