Drug metabolism in human liver microsomes assessed as CYP3A4/5-mediated (2S)-methyl 2-(2-chlorophenyl)-2-(3-hydroxy-2,3,6,7-tetrahydrothieno[3,2-c]pyr...

Basic Information

ID: ALA2174396

Type: ADME

Description: Drug metabolism in human liver microsomes assessed as CYP3A4/5-mediated (2S)-methyl 2-(2-chlorophenyl)-2-(3-hydroxy-2,3,6,7-tetrahydrothieno[3,2-c]pyridin-5(4H)-yl)acetate formation at 50 uM

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target:  Cytochrome P450 3A4/3A5(ALA2111472)

Document:  ALA2169782

Drug metabolism in human liver microsomes assessed as CYP3A4/5-mediated (2S)-methyl 2-(2-chlorophenyl)-2-(3-hydroxy-2,3,6,7-tetrahydrothieno[3,2-c]pyridin-5(4H)-yl)acetate formation at 50 uM: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
321.833.673.67