ID: ALA2174396
Type: ADME
Description: Drug metabolism in human liver microsomes assessed as CYP3A4/5-mediated (2S)-methyl 2-(2-chlorophenyl)-2-(3-hydroxy-2,3,6,7-tetrahydrothieno[3,2-c]pyridin-5(4H)-yl)acetate formation at 50 uM
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: Cytochrome P450 3A4/3A5(ALA2111472)
Document: ALA2169782
Drug metabolism in human liver microsomes assessed as CYP3A4/5-mediated (2S)-methyl 2-(2-chlorophenyl)-2-(3-hydroxy-2,3,6,7-tetrahydrothieno[3,2-c]pyridin-5(4H)-yl)acetate formation at 50 uM: 1
Bioactivity
Activity Types for Assay ALA2174396
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
321.83 | 3.67 | 3.67 |