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Prodrug activation in human liver microsomes assessed as CYP3A4/5-mediated 2-oxo-clopidogrel formation at 50 uM

Basic Information

ID: ALA2174402

Type: ADME

Description: Prodrug activation in human liver microsomes assessed as CYP3A4/5-mediated 2-oxo-clopidogrel formation at 50 uM

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target:  Cytochrome P450 3A4/3A5(ALA2111472)

Document:  ALA2169782

Prodrug activation in human liver microsomes assessed as CYP3A4/5-mediated 2-oxo-clopidogrel formation at 50 uM: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA2174402

Drug metabolism

Total(1)

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
321.833.673.67
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