Basic Information
ID: ALA2174547
Type: Binding
Description: Inhibition of 5-lipoxygenase-mediated 5(S)-H(p)ETE formation in fMLP-stimulated human PMNL incubated 10 mins prior to fMLP challenge
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2174547
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.09 | 8.01 | 8.01 |
| 283.33 | 3.73 | 3.73 |
| 410.50 | 3.90 | 3.90 |
| 466.60 | 5.46 | 5.46 |
| 602.60 | 7.49 | 7.49 |
| 634.60 | 7.25 | 7.25 |
| 556.60 | 5.27 | 5.27 |
| 516.62 | 5.20 | 5.20 |
| 478.66 | 5.58 | 5.58 |
| 506.75 | 7.69 | 7.69 |
| 478.70 | 6.91 | 6.91 |
| 450.65 | 6.13 | 6.13 |
| 394.54 | 4.57 | 4.57 |
| 398.57 | 5.06 | 5.06 |
| 494.66 | 6.24 | 6.24 |
| 486.59 | 5.64 | 5.64 |
| 522.71 | 7.02 | 7.02 |
| 494.66 | 6.24 | 6.24 |
| 438.55 | 5.37 | 5.37 |
| 526.66 | 5.47 | 5.47 |
| 438.55 | 4.67 | 4.67 |
| 494.66 | 6.07 | 6.07 |
| 446.59 | 6.36 | 6.36 |
| 444.57 | 6.59 | 6.59 |
| 464.63 | 6.67 | 6.67 |
| 448.56 | 5.95 | 5.95 |
| 446.59 | 6.36 | 6.36 |
| 446.59 | 6.36 | 6.36 |
| 446.59 | 6.36 | 6.36 |
| 446.59 | 6.36 | 6.36 |
| 444.57 | 6.59 | 6.59 |
| 456.67 | 8.04 | 8.04 |
| 580.57 | 8.63 | 8.63 |
| 552.51 | 8.54 | 8.54 |
| 504.59 | 8.29 | 8.29 |
| 444.57 | 6.59 | 6.59 |