Basic Information
ID: ALA2175187
Type: Binding
Description: Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction in nucleus after 30 mins by EMSA
Organism: Mus musculus
Cell type: NIH3T3
Activity Charts
Bioactivity
Activity Types for Assay ALA2175187
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 503.45 | 1.99 | 1.99 |
| 365.36 | 1.74 | 1.74 |
| 550.68 | 5.30 | 5.30 |
| 663.75 | 5.69 | 5.69 |
| 716.84 | 4.69 | 4.69 |
| 524.58 | 6.34 | 6.34 |
| 537.63 | 5.39 | 5.39 |
| 652.77 | 5.51 | 5.51 |
| 532.53 | 6.70 | 6.70 |
| 480.41 | 4.66 | 4.66 |
| 496.48 | 5.13 | 5.13 |
| 508.51 | 5.87 | 5.87 |