Basic Information
ID: ALA2175366
Type: Binding
Description: Inhibition of Trypanosoma brucei recombinant TbrPDEB1 expressed in Sf21 insect cells assessed as reduction of [3H]-cAMP hydrolysis by scintillation proximity assay
Organism: Trypanosoma brucei
Activity Charts
Bioactivity
Activity Types for Assay ALA2175366
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 275.35 | 2.62 | 2.62 |
| 503.64 | 6.10 | 6.10 |
| 546.67 | 5.41 | 5.41 |
| 367.45 | 3.65 | 3.65 |
| 371.44 | 3.55 | 3.55 |
| 449.55 | 4.79 | 4.79 |
| 492.58 | 4.09 | 4.09 |
| 445.56 | 5.44 | 5.44 |
| 450.58 | 5.58 | 5.58 |
| 464.61 | 5.62 | 5.62 |
| 470.61 | 6.72 | 6.72 |
| 421.54 | 4.96 | 4.96 |
| 425.53 | 4.87 | 4.87 |
| 276.34 | 2.38 | 2.38 |
| 330.43 | 3.70 | 3.70 |
| 252.70 | 2.21 | 2.21 |
| 294.78 | 3.33 | 3.33 |
| 348.87 | 4.64 | 4.64 |
| 297.15 | 2.32 | 2.32 |
| 339.23 | 3.44 | 3.44 |
| 393.32 | 4.75 | 4.75 |
| 391.47 | 4.13 | 4.13 |
| 396.49 | 4.26 | 4.26 |
| 410.51 | 4.31 | 4.31 |
| 416.52 | 5.41 | 5.41 |
| 302.37 | 2.88 | 2.88 |
| 398.55 | 5.31 | 5.31 |
| 324.38 | 3.13 | 3.13 |
| 338.41 | 3.48 | 3.48 |
| 366.46 | 4.26 | 4.26 |
| 420.55 | 5.57 | 5.57 |