Basic Information
ID: ALA2175529
Type: Binding
Description: Inhibition of TNFalpha-induced human NFkappaB activity in HEK293 cells at 50 uM incubated for 6 hrs followed by compound wash out measured after 5 mins by by luciferase assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2175529
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.23 | 3.91 | 3.91 |
| 349.35 | 2.47 | 2.47 |
| 433.51 | 4.17 | 4.17 |
| 447.54 | 4.19 | 4.19 |
| 435.52 | 4.02 | 4.02 |
| 347.42 | 2.63 | 2.63 |
| 335.41 | 2.45 | 2.45 |
| 333.39 | 2.60 | 2.60 |
| 363.37 | 2.73 | 2.73 |
| 333.39 | 2.40 | 2.40 |
| 335.41 | 2.26 | 2.26 |
| 319.36 | 2.14 | 2.14 |
| 321.38 | 1.99 | 1.99 |
| 361.40 | 2.52 | 2.52 |
| 363.42 | 2.37 | 2.37 |
| 320.35 | 2.18 | 2.18 |
| 322.36 | 2.03 | 2.03 |
| 362.39 | 2.55 | 2.55 |
| 338.79 | 3.42 | 3.42 |
| 387.40 | 3.87 | 3.87 |
| 449.46 | 4.04 | 4.04 |
| 419.48 | 3.71 | 3.71 |
| 391.38 | 2.65 | 2.65 |
| 361.40 | 2.32 | 2.32 |
| 350.33 | 2.50 | 2.50 |