Basic Information
ID: ALA2175616
Type: Binding
Description: Inhibition of human recombinant DOT1L catalytic domain amino acid (1 to 472) using [3H]-SAM after 30 mins by scintillation counter
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2175616
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.42 | -1.44 | -1.44 |
| 373.44 | 0.96 | 0.96 |
| 327.37 | -1.25 | -1.25 |
| 355.38 | -0.76 | -0.76 |
| 326.38 | -1.28 | -1.28 |
| 340.41 | -0.89 | -0.89 |
| 357.37 | -0.79 | -0.79 |
| 357.37 | -0.79 | -0.79 |
| 362.42 | -0.12 | -0.12 |
| 346.35 | -0.59 | -0.59 |
| 411.47 | 0.30 | 0.30 |
| 440.53 | 0.68 | 0.68 |
| 457.49 | -0.07 | -0.07 |
| 474.54 | 1.08 | 1.08 |
| 412.47 | -0.10 | -0.10 |
| 499.57 | 1.05 | 1.05 |
| 458.54 | 0.51 | 0.51 |
| 444.52 | 0.58 | 0.58 |
| 494.58 | 1.73 | 1.73 |
| 458.54 | 1.57 | 1.57 |
| 460.52 | 1.40 | 1.40 |
| 473.56 | 0.65 | 0.65 |
| 463.52 | 0.24 | 0.24 |
| 425.52 | -0.14 | -0.14 |
| 465.58 | 0.78 | 0.78 |
| 459.53 | 0.97 | 0.97 |
| 445.51 | 0.58 | 0.58 |
| 473.56 | 1.36 | 1.36 |
| 501.61 | 2.10 | 2.10 |
| 529.67 | 2.73 | 2.73 |
| 493.98 | 1.63 | 1.63 |
| 538.43 | 1.74 | 1.74 |
| 585.43 | 1.58 | 1.58 |
| 527.53 | 1.99 | 1.99 |
| 543.53 | 1.87 | 1.87 |
| 487.59 | 1.54 | 1.54 |
| 487.59 | 1.54 | 1.54 |
| 495.51 | 1.25 | 1.25 |
| 595.53 | 3.01 | 3.01 |
| 509.59 | 2.13 | 2.13 |
| 540.67 | 2.25 | 2.25 |
| 554.70 | 2.71 | 2.71 |
| 580.73 | 3.26 | 3.26 |
| 630.79 | 4.28 | 4.28 |
| 374.43 | 0.40 | 0.40 |
| 398.45 | -0.98 | -0.98 |
| 424.48 | -0.42 | -0.42 |
| 424.48 | -0.44 | -0.44 |
| 426.50 | -0.20 | -0.20 |
| 440.53 | 0.19 | 0.19 |
| 440.53 | 0.19 | 0.19 |
| 454.55 | 0.44 | 0.44 |
| 454.55 | 0.44 | 0.44 |
| 474.54 | 0.59 | 0.59 |
| 323.36 | -2.03 | -2.03 |
| 304.31 | -1.75 | -1.75 |