Basic Information
ID: ALA2175939
Type: Binding
Description: Transrepressional activity at LXR in human TPA-activated THP1 cells assessed as inhibition of LPS-induced IL6 production incubated for 6 hrs prior to LPS-challenge measured after 18 hrs by ELISA
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA2175939
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.34 | 4.76 | 4.76 |
| 490.27 | 6.82 | 6.82 |
| 251.28 | 3.04 | 3.04 |
| 401.31 | 4.65 | 4.65 |