Assay Report Card

Basic Information

ID: ALA2175964

Type: Binding

Description: Transrepressional activity at LXR in C57BL/6J mouse peritoneal macrophages assessed as inhibition of LPS-induced IL-6 mRNA expression at 10 uM incubated for 6 hr prior to LPS-challenge measured after 18 hrs by RT-PCR analysis

Organism: Mus musculus

Strain: C57BL/6J

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
401.314.654.65
263.343.903.90