Basic Information
ID: ALA2176143
Type: Functional
Description: Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum NF54 infected in human erythrocytes assessed as inhibition of [3H]hypoxanthine incorporation incubated for 48 hrs prior to [3H]hypoxanthine addition measured after 48 hrs by liquid scintillation counting
Organism: Plasmodium falciparum
Strain: NF54
Activity Charts
Bioactivity
Activity Types for Assay ALA2176143
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.88 | 4.81 | 4.81 |
| 462.42 | 7.34 | 7.34 |
| 462.42 | 7.34 | 7.34 |
| 512.87 | 7.23 | 7.23 |
| 492.45 | 7.35 | 7.35 |
| 476.00 | 6.83 | 6.83 |
| 508.45 | 6.58 | 6.58 |
| 530.42 | 8.36 | 8.36 |
| 496.87 | 7.99 | 7.99 |
| 480.41 | 7.48 | 7.48 |
| 492.45 | 7.35 | 7.35 |
| 476.00 | 6.83 | 6.83 |
| 513.97 | 7.84 | 7.84 |
| 492.45 | 7.35 | 7.35 |
| 656.10 | 9.79 | 9.79 |
| 459.38 | 6.99 | 6.99 |
| 477.44 | 6.15 | 6.15 |
| 473.02 | 5.50 | 5.50 |
| 477.44 | 6.15 | 6.15 |
| 491.47 | 6.49 | 6.49 |
| 567.56 | 8.06 | 8.06 |
| 868.74 | 13.12 | 13.12 |
| 531.53 | 7.05 | 7.05 |
| 642.07 | 8.90 | 8.90 |
| 673.48 | 9.92 | 9.92 |
| 496.87 | 7.99 | 7.99 |
| 480.41 | 7.48 | 7.48 |