Basic Information
ID: ALA2176208
Type: Binding
Description: Inhibition of human recombinant SIRT1 expressed in Escherichia coli cells using acetylated Lys side chain amino acids 379-382 (Arg-His-Lys-Lys(Ac)) p53 conjugated with aminomethylcoumarin as substrate by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2176208
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 248.71 | 2.73 | 2.73 |
| 434.28 | 6.35 | 6.35 |
| 340.34 | 3.60 | 3.60 |
| 278.27 | 2.14 | 2.14 |
| 292.29 | 2.63 | 2.63 |
| 306.32 | 3.02 | 3.02 |
| 304.31 | 2.79 | 2.79 |
| 320.35 | 3.41 | 3.41 |
| 346.39 | 4.11 | 4.11 |
| 354.37 | 3.66 | 3.66 |
| 228.21 | 0.99 | 0.99 |
| 242.23 | 1.47 | 1.47 |
| 256.26 | 1.86 | 1.86 |
| 270.29 | 2.25 | 2.25 |