Basic Information
ID: ALA2176517
Type: Binding
Description: Transrepressional activity at LXR in human TPA-activated THP1 cells assessed as inhibition of LPS-induced IL6 production at 10 uM incubated for 6 hrs prior to LPS-challenge measured after 18 hrs by ELISA
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA2176517
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.34 | 4.76 | 4.76 |
| 377.28 | 4.28 | 4.28 |
| 490.27 | 6.82 | 6.82 |
| 397.47 | 5.19 | 5.19 |
| 397.47 | 5.19 | 5.19 |
| 280.28 | 3.25 | 3.25 |
| 250.30 | 2.92 | 2.92 |
| 251.28 | 3.04 | 3.04 |
| 265.31 | 2.83 | 2.83 |
| 279.30 | 3.04 | 3.04 |
| 277.32 | 3.54 | 3.54 |
| 391.27 | 4.38 | 4.38 |
| 403.32 | 4.37 | 4.37 |
| 401.31 | 4.65 | 4.65 |
| 249.31 | 3.65 | 3.65 |
| 263.34 | 3.90 | 3.90 |
| 319.45 | 5.46 | 5.46 |
| 277.37 | 4.46 | 4.46 |
| 291.39 | 4.64 | 4.64 |