Basic Information
ID: ALA2176518
Type: Binding
Description: Transrepressional activity at LXR in human TPA-activated THP1 cells assessed as inhibition of LPS-induced IL6 production at 30 uM incubated for 6 hrs prior to LPS-challenge measured after 18 hrs by ELISA
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA2176518
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.45 | 5.27 | 5.27 |
| 375.27 | 4.00 | 4.00 |
| 235.29 | 3.34 | 3.34 |
| 403.61 | 7.80 | 7.80 |
| 383.45 | 5.27 | 5.27 |