Basic Information
ID: ALA2182559
Type: Binding
Description: Inhibition of His6-tagged BRD3 expressed in Escherichia coli assessed as inhibition of binding to SGRG-K(Ac)-GG-K(Ac)-GLG-K(Ac)-GGA-K(Ac)-RHGSGSK-biotin after 1 hr by TR-FRET assay
Activity Charts
Bioactivity
Activity Types for Assay ALA2182559
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 423.90 | 3.66 | 3.66 |
| 423.48 | 4.35 | 4.35 |
| 266.32 | 1.91 | 1.91 |
| 294.38 | 2.57 | 2.57 |
| 364.47 | 3.53 | 3.53 |
| 378.49 | 3.92 | 3.92 |
| 320.41 | 3.05 | 3.05 |
| 334.44 | 3.44 | 3.44 |
| 335.43 | 1.86 | 1.86 |
| 351.43 | 1.56 | 1.56 |
| 336.41 | 2.29 | 2.29 |
| 352.41 | 1.99 | 1.99 |
| 349.46 | 2.30 | 2.30 |
| 365.46 | 2.00 | 2.00 |
| 349.46 | 2.30 | 2.30 |
| 365.46 | 2.00 | 2.00 |
| 292.36 | 2.40 | 2.40 |
| 336.41 | 2.88 | 2.88 |
| 448.59 | 2.46 | 2.46 |
| 463.60 | 3.28 | 3.28 |
| 306.39 | 2.71 | 2.71 |
| 322.39 | 2.41 | 2.41 |
| 334.44 | 3.49 | 3.49 |
| 350.44 | 3.19 | 3.19 |
| 348.47 | 3.88 | 3.88 |
| 342.42 | 4.07 | 4.07 |
| 358.42 | 3.77 | 3.77 |
| 376.87 | 4.72 | 4.72 |
| 392.86 | 4.42 | 4.42 |
| 376.87 | 4.72 | 4.72 |
| 376.87 | 4.72 | 4.72 |
| 372.45 | 4.08 | 4.08 |
| 388.45 | 3.78 | 3.78 |
| 372.45 | 4.08 | 4.08 |
| 388.45 | 3.78 | 3.78 |
| 372.45 | 4.08 | 4.08 |
| 388.45 | 3.78 | 3.78 |
| 356.45 | 3.75 | 3.75 |
| 372.45 | 3.45 | 3.45 |
| 370.47 | 3.79 | 3.79 |
| 384.50 | 4.18 | 4.18 |
| 324.40 | 2.19 | 2.19 |
| 324.40 | 1.93 | 1.93 |
| 322.43 | 3.34 | 3.34 |