Basic Information
ID: ALA2183078
Type: Binding
Description: Inhibition of BACE1 in human SH-SY5Y cells assessed as inhibition of sAPPbeta release after 16 hrs by immunoassay
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA2183078
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 476.56 | 4.76 | 4.76 |
| 456.50 | 4.53 | 4.53 |
| 463.52 | 4.26 | 4.26 |
| 494.55 | 4.90 | 4.90 |
| 425.51 | 4.09 | 4.09 |
| 515.98 | 4.63 | 4.63 |
| 467.40 | 4.85 | 4.85 |
| 363.42 | 3.55 | 3.55 |
| 431.42 | 4.57 | 4.57 |
| 381.41 | 3.69 | 3.69 |
| 381.41 | 3.69 | 3.69 |
| 398.42 | 4.43 | 4.43 |
| 449.41 | 4.71 | 4.71 |
| 473.43 | 5.18 | 5.18 |
| 467.40 | 4.85 | 4.85 |
| 467.40 | 4.85 | 4.85 |
| 409.47 | 4.31 | 4.31 |
| 421.48 | 4.57 | 4.57 |
| 411.44 | 3.70 | 3.70 |
| 431.42 | 4.63 | 4.63 |
| 431.42 | 4.63 | 4.63 |
| 449.41 | 4.77 | 4.77 |
| 468.48 | 5.60 | 5.60 |
| 410.45 | 4.30 | 4.30 |
| 439.49 | 4.31 | 4.31 |
| 449.49 | 4.48 | 4.48 |
| 425.47 | 3.30 | 3.30 |
| 439.49 | 3.78 | 3.78 |