Assay Report Card

Basic Information

ID: ALA2184167

Type: ADME

Description: Cellular uptake in human NCI-H292 cells assessed as compound retention at 3 to 20 uM incubated for 3 hrs followed by drug washout measured after 3 hrs by LC-MS/MS analysis relative to initial drug accumulation

Organism: Homo sapiens

Cell type: NCI-H292

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
749.001.901.90
762.981.741.74
747.962.442.44
590.800.980.98
876.142.632.63
918.264.144.14
918.264.144.14
433.590.530.53