Basic Information
ID: ALA2184421
Type: Binding
Description: Positive allosteric modulation activity at rat mGlu2R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assay relative to glutamate
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: HEK293
Target: Metabotropic glutamate receptor 2(ALA2851)
Document: ALA2177081
Positive allosteric modulation activity at rat mGlu2R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assay relative to glutamate: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2184421
%max
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.57 | 6.79 | 6.79 |
| 461.95 | 6.18 | 6.18 |
| 479.99 | 6.78 | 6.78 |
| 425.89 | 5.20 | 5.20 |
| 465.96 | 6.07 | 6.07 |
| 465.96 | 6.39 | 6.39 |
| 467.97 | 6.32 | 6.32 |
| 451.93 | 6.00 | 6.00 |
| 482.00 | 6.71 | 6.71 |
| 457.53 | 5.54 | 5.54 |
| 443.50 | 5.23 | 5.23 |
| 487.55 | 5.55 | 5.55 |
| 461.95 | 6.18 | 6.18 |
| 461.95 | 6.18 | 6.18 |
| 441.53 | 5.84 | 5.84 |
| 445.49 | 5.67 | 5.67 |
| 457.53 | 5.54 | 5.54 |
| 383.49 | 5.83 | 5.83 |
| 435.93 | 6.62 | 6.62 |
| 469.48 | 6.99 | 6.99 |
| 459.57 | 6.43 | 6.43 |
| 490.54 | 6.03 | 6.03 |
| 463.53 | 6.26 | 6.26 |
| 507.06 | 6.78 | 6.78 |
| 431.92 | 6.27 | 6.27 |