Basic Information
ID: ALA2184478
Type: Functional
Description: Antagonist activity at human P2X4 receptor expressed in 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubated at 10 uM for 30 mins before ATP treatment by Fluo-4 AM fluorescence method
Organism: Homo sapiens
Cell type: 1321-N1
Activity Charts
Bioactivity
Activity Types for Assay ALA2184478
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 213.24 | 2.64 | 2.64 |
| 317.34 | 5.27 | 5.27 |
| 362.34 | 5.18 | 5.18 |
| 347.44 | 6.03 | 6.03 |
| 213.67 | 4.04 | 4.04 |
| 363.46 | 5.62 | 5.62 |
| 222.24 | 1.26 | 1.26 |
| 243.26 | 3.14 | 3.14 |
| 248.28 | 1.34 | 1.34 |
| 239.27 | 2.73 | 2.73 |
| 269.30 | 3.22 | 3.22 |
| 412.37 | 4.88 | 4.88 |
| 452.51 | 5.65 | 5.65 |
| 301.35 | 4.70 | 4.70 |
| 337.40 | 4.46 | 4.46 |
| 226.24 | 3.01 | 3.01 |
| 240.26 | 3.27 | 3.27 |
| 268.32 | 4.05 | 4.05 |
| 308.38 | 4.97 | 4.97 |
| 311.39 | 3.59 | 3.59 |
| 316.36 | 4.84 | 4.84 |
| 385.25 | 6.15 | 6.15 |
| 296.33 | 3.38 | 3.38 |
| 309.37 | 3.30 | 3.30 |
| 273.34 | 5.13 | 5.13 |
| 225.25 | 3.48 | 3.48 |