Basic Information
ID: ALA2184479
Type: Functional
Description: Antagonist activity at human P2X4 receptor expressed in 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx compound preincubated for 30 mins before ATP treatment by Fluo-4 AM fluorescence method
Organism: Homo sapiens
Cell type: 1321-N1
Activity Charts
Bioactivity
Activity Types for Assay ALA2184479
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 329.37 | 3.33 | 3.33 |
| 507.18 | -1.63 | -1.63 |
| 553.28 | -0.91 | -0.91 |
| 213.24 | 2.64 | 2.64 |
| 285.35 | 4.20 | 4.20 |
| 315.37 | 4.21 | 4.21 |
| 717.26 | -1.09 | -1.09 |
| 241.25 | 3.70 | 3.70 |
| 269.30 | 4.48 | 4.48 |
| 317.34 | 5.27 | 5.27 |
| 331.37 | 5.58 | 5.58 |
| 351.79 | 5.92 | 5.92 |
| 362.34 | 5.18 | 5.18 |
| 347.37 | 5.28 | 5.28 |
| 331.37 | 5.31 | 5.31 |
| 347.44 | 6.03 | 6.03 |
| 213.67 | 4.04 | 4.04 |
| 299.33 | 3.84 | 3.84 |
| 294.35 | 3.46 | 3.46 |
| 299.37 | 4.51 | 4.51 |
| 330.34 | 4.11 | 4.11 |
| 363.46 | 5.62 | 5.62 |
| 222.24 | 1.26 | 1.26 |
| 305.42 | 3.81 | 3.81 |
| 243.26 | 3.14 | 3.14 |
| 248.28 | 1.34 | 1.34 |
| 239.27 | 2.73 | 2.73 |
| 269.30 | 3.22 | 3.22 |
| 412.37 | 4.88 | 4.88 |
| 452.51 | 5.65 | 5.65 |
| 302.33 | 4.35 | 4.35 |
| 301.35 | 4.70 | 4.70 |
| 337.40 | 4.63 | 4.63 |
| 337.40 | 4.46 | 4.46 |
| 226.24 | 3.01 | 3.01 |
| 240.26 | 3.27 | 3.27 |
| 268.32 | 4.05 | 4.05 |
| 308.38 | 4.97 | 4.97 |
| 311.39 | 3.59 | 3.59 |
| 323.40 | 3.73 | 3.73 |
| 316.36 | 4.84 | 4.84 |
| 350.81 | 5.49 | 5.49 |
| 385.25 | 6.15 | 6.15 |
| 330.39 | 4.88 | 4.88 |
| 254.29 | 3.61 | 3.61 |
| 282.34 | 4.39 | 4.39 |
| 310.40 | 5.17 | 5.17 |
| 310.40 | 5.17 | 5.17 |
| 296.33 | 3.38 | 3.38 |
| 294.35 | 4.54 | 4.54 |
| 309.37 | 3.30 | 3.30 |
| 355.19 | 3.98 | 3.98 |
| 273.34 | 5.13 | 5.13 |
| 245.66 | 4.29 | 4.29 |
| 225.25 | 3.48 | 3.48 |
| 287.32 | 4.77 | 4.77 |
| 332.32 | 4.68 | 4.68 |
| 321.76 | 5.42 | 5.42 |