Assay Report Card

Basic Information

ID: ALA2184480

Type: Functional

Description: Antagonist activity at human P2X4 receptor expressed in 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubated at IC50 for 30 mins before ATP treatment by Fluo-4 AM fluorescence method

Organism: Homo sapiens

Cell type: 1321-N1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
331.375.585.58
351.795.925.92
347.375.285.28
363.465.625.62
337.404.634.63
330.394.884.88
294.354.544.54
287.324.774.77
332.324.684.68
321.765.425.42