Basic Information
ID: ALA2184768
Type: Binding
Description: Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2
Format: BAO_0000357
Target: MAP kinase p38 alpha(ALA260)
Document: ALA2177073
Inhibition of MAP kinase p38alpha assessed as phosphorylation of ATF-2: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2184768
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.44 | 4.68 | 4.68 |
| 314.39 | 4.34 | 4.34 |
| 388.44 | 5.73 | 5.73 |
| 406.43 | 5.87 | 5.87 |
| 388.44 | 5.73 | 5.73 |
| 438.45 | 6.61 | 6.61 |
| 455.56 | 5.43 | 5.43 |
| 434.50 | 6.11 | 6.11 |
| 438.46 | 5.95 | 5.95 |
| 418.50 | 6.01 | 6.01 |
| 432.52 | 6.32 | 6.32 |
| 436.49 | 6.15 | 6.15 |
| 432.52 | 6.32 | 6.32 |
| 436.49 | 6.15 | 6.15 |
| 370.45 | 5.59 | 5.59 |
| 384.48 | 5.90 | 5.90 |
| 388.44 | 5.73 | 5.73 |
| 384.48 | 5.90 | 5.90 |
| 388.44 | 5.73 | 5.73 |
| 420.47 | 5.81 | 5.81 |
| 434.50 | 6.11 | 6.11 |
| 438.46 | 5.95 | 5.95 |
| 434.50 | 6.11 | 6.11 |
| 438.46 | 5.95 | 5.95 |
| 418.50 | 6.01 | 6.01 |
| 382.46 | 4.65 | 4.65 |
| 474.60 | 7.31 | 7.31 |
| 488.63 | 7.62 | 7.62 |
| 440.52 | 6.18 | 6.18 |
| 505.57 | 5.64 | 5.64 |
| 432.52 | 5.94 | 5.94 |
| 446.55 | 6.33 | 6.33 |
| 382.46 | 5.11 | 5.11 |
| 408.46 | 5.61 | 5.61 |
| 408.46 | 5.61 | 5.61 |
| 426.45 | 5.74 | 5.74 |
| 424.53 | 6.07 | 6.07 |
| 424.53 | 6.07 | 6.07 |
| 402.47 | 5.66 | 5.66 |
| 416.50 | 6.05 | 6.05 |
| 334.42 | 4.69 | 4.69 |
| 360.41 | 5.18 | 5.18 |
| 378.40 | 5.32 | 5.32 |
| 376.48 | 5.65 | 5.65 |
| 390.51 | 5.96 | 5.96 |
| 394.47 | 5.79 | 5.79 |
| 408.50 | 6.10 | 6.10 |
| 410.43 | 5.40 | 5.40 |
| 426.50 | 5.87 | 5.87 |
| 440.52 | 6.18 | 6.18 |
| 444.49 | 6.01 | 6.01 |
| 458.51 | 6.31 | 6.31 |
| 370.45 | 5.59 | 5.59 |
| 334.42 | 4.23 | 4.23 |
| 426.56 | 6.89 | 6.89 |
| 440.59 | 7.20 | 7.20 |
| 420.47 | 5.81 | 5.81 |
| 432.52 | 6.32 | 6.32 |
| 448.52 | 6.02 | 6.02 |
| 436.49 | 6.15 | 6.15 |
| 436.49 | 6.15 | 6.15 |
| 486.49 | 7.03 | 7.03 |
| 517.63 | 6.16 | 6.16 |
| 440.59 | 7.20 | 7.20 |
| 444.55 | 7.03 | 7.03 |
| 384.48 | 5.90 | 5.90 |
| 400.48 | 5.60 | 5.60 |
| 400.48 | 5.60 | 5.60 |
| 400.48 | 5.60 | 5.60 |