Basic Information
ID: ALA2185388
Type: Binding
Description: Inhibition of mouse recombinant FAP expressed in HEK293 cells assessed as pNA release from Ala-Pro-p-nitroanilide pre-incubated with enzyme for 15 mins prior to substrate addition by fluorescence technique
Organism: Mus musculus
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2185388
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 314.43 | 2.62 | 2.62 |
| 339.44 | 2.51 | 2.51 |
| 302.37 | 2.41 | 2.41 |
| 355.44 | 2.91 | 2.91 |
| 457.58 | 3.73 | 3.73 |
| 510.64 | 3.09 | 3.09 |
| 380.45 | 2.80 | 2.80 |
| 535.65 | 2.98 | 2.98 |
| 510.64 | 3.09 | 3.09 |
| 445.52 | 3.52 | 3.52 |
| 457.58 | 3.73 | 3.73 |
| 475.57 | 3.87 | 3.87 |
| 493.56 | 4.01 | 4.01 |
| 493.56 | 4.01 | 4.01 |
| 492.02 | 4.39 | 4.39 |
| 536.47 | 4.49 | 4.49 |
| 446.51 | 2.91 | 2.91 |
| 458.57 | 3.13 | 3.13 |
| 501.63 | 3.78 | 3.78 |
| 446.98 | 1.52 | 1.52 |
| 438.58 | 2.13 | 2.13 |
| 480.61 | 1.90 | 1.90 |
| 579.75 | 3.12 | 3.12 |
| 479.63 | 1.47 | 1.47 |
| 461.57 | 2.47 | 2.47 |
| 343.39 | 2.70 | 2.70 |
| 355.44 | 2.91 | 2.91 |
| 369.43 | 1.85 | 1.85 |
| 441.61 | ||
| 421.55 | 2.94 | 2.94 |
| 463.63 | 4.11 | 4.11 |
| 498.58 | 2.88 | 2.88 |