Basic Information
ID: ALA2185507
Type: Binding
Description: Inhibition of BACE1 expressed in human H4 cells assessed as reduction in sAPPbeta level at 10 uM incubated for 16 hrs in presence of 25 uM metalloprotease inhibitor batimastat by HPLAP-APP reporter assay
Organism: Homo sapiens
Cell type: H4
Activity Charts
Bioactivity
Activity Types for Assay ALA2185507
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 578.74 | 3.03 | 3.03 |
| 461.60 | 3.20 | 3.20 |
| 1010.22 | ||
| 1024.25 | ||
| 707.87 | 1.75 | 1.75 |
| 836.00 | 0.50 | 0.50 |
| 979.19 | 0.35 | 0.35 |
| 868.04 | 0.27 | 0.27 |
| 957.18 | 1.50 | 1.50 |
| 909.14 | 0.71 | 0.71 |
| 965.16 | 0.01 | 0.01 |
| 1041.26 | ||
| 907.12 | 0.81 | 0.81 |
| 1007.24 |