Basic Information
ID: ALA2186227
Type: ADME
Description: Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate after 10 mins
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: Cytochrome P450 2C19(ALA3622)
Document: ALA2176970
Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate after 10 mins: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2186227
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 420.48 | 4.25 | 4.25 |
| 420.48 | 3.99 | 3.99 |
| 497.56 | 5.06 | 5.06 |
| 571.62 | 5.76 | 5.76 |