Basic Information
ID: ALA2186395
Type: Functional
Description: Antagonist activity at NMDA receptor GluN2B subunit in FVB mouse CA1 pyramidal neurons assessed as decrease in EPSC amplitude at holding potential of -60 mV at 100 nM measured at 5 mins by patch clamp electrophysiological assay in presence of Mg2+ free ACSF containing CNQX, glycine, bicuculline relative to control
Organism: Mus musculus
Strain: FVB
Cell type: Pyramidal neuron
Activity Charts
Bioactivity
Activity Types for Assay ALA2186395
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.55 | 3.68 | 3.68 |