Assay Report Card

Basic Information

ID: ALA2187099

Type: Functional

Description: Agonist activity at human TLR8 expressed in HEK293 cells assessed as induction of NF-kappaB activity by measuring extracellular secreted alkaline phosphatase by HEK-blue reporter gene assay

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
243.333.383.38
270.292.352.35
339.444.974.97
357.435.115.11
384.444.884.88
622.736.936.93
327.393.373.37
352.444.514.51
353.433.913.91
360.424.384.38
361.413.773.77
442.565.525.52
359.434.984.98
326.403.983.98
340.434.374.37
312.373.593.59
340.434.374.37
382.515.395.39
356.50
383.452.512.51
356.382.742.74
398.463.913.91
420.414.404.40
376.424.524.52
394.865.475.47
374.444.944.94
326.403.983.98