Assay Report Card

Basic Information

ID: ALA2187461

Type: Functional

Description: Agonist activity at alpha6/alpha3beta2beta3 nAChR in Sprague-Dawley rat striatal synaptosomes assessed as induction of dopamine release relative to 10 uM nicotine

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Tissue: Brain

Subcellular Fraction: Synaptosomes

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
200.292.092.09
200.292.092.09
214.312.442.44
214.312.442.44
258.372.882.88
272.393.223.22
292.383.893.89