Basic Information
ID: ALA2187468
Type: Functional
Description: Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPR
Organism: Homo sapiens
Cell type: SH-EP1
Activity Charts
Bioactivity
Activity Types for Assay ALA2187468
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 235.72 | 2.14 | 2.14 |
| 201.27 | 1.49 | 1.49 |
| 225.30 | 1.97 | 1.97 |
| 218.28 | 2.23 | 2.23 |
| 232.30 | 2.58 | 2.58 |
| 234.73 | 2.75 | 2.75 |
| 244.34 | 2.45 | 2.45 |
| 214.31 | 2.40 | 2.40 |
| 276.38 | 3.76 | 3.76 |
| 234.73 | 2.75 | 2.75 |
| 276.38 | 3.76 | 3.76 |
| 225.30 | 1.97 | 1.97 |
| 200.29 | 2.09 | 2.09 |
| 200.29 | 2.09 | 2.09 |
| 214.31 | 2.44 | 2.44 |
| 214.31 | 2.44 | 2.44 |
| 230.31 | 2.10 | 2.10 |
| 244.34 | 2.45 | 2.45 |
| 258.37 | 2.88 | 2.88 |
| 272.39 | 3.22 | 3.22 |
| 292.38 | 3.89 | 3.89 |
| 306.41 | 4.23 | 4.23 |
| 218.28 | 2.23 | 2.23 |
| 218.28 | 2.23 | 2.23 |
| 225.30 | 1.97 | 1.97 |