Assay Report Card

Basic Information

ID: ALA2187471

Type: Functional

Description: Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPR relative to 10 uM nicotine

Organism: Homo sapiens

Cell type: SH-EP1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
235.722.142.14
201.271.491.49
225.301.971.97
218.282.232.23
232.302.582.58
234.732.752.75
244.342.452.45
214.312.402.40
276.383.763.76
234.732.752.75
276.383.763.76
225.301.971.97
200.292.092.09
200.292.092.09
214.312.442.44
214.312.442.44
230.312.102.10
244.342.452.45
258.372.882.88
272.393.223.22
292.383.893.89
306.414.234.23
218.282.232.23
218.282.232.23
225.301.971.97