Basic Information
ID: ALA2187522
Type: ADME
Description: Activation of NPFF2R in Sprague-Dawley rat cardiomyocytes assessed inhibition of cardiac function by measuring decrease in departure velocity at 10 nM incubated for 20 mins relative to human RFRP-1
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Heart
Activity Charts
Bioactivity
Activity Types for Assay ALA2187522
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 969.16 | -3.45 | -3.45 |
| 1352.63 | ||
| 1414.70 | ||
| 1385.71 | ||
| 1386.65 | ||
| 1402.69 | ||
| 1386.65 | ||
| 1343.62 | ||
| 1352.63 | ||
| 1297.53 | ||
| 1200.41 | ||
| 1402.69 | ||
| 1362.67 | ||
| 1412.73 | ||
| 1063.27 | ||
| 976.19 | -1.57 | -1.57 |
| 829.02 | -2.29 | -2.29 |
| 757.94 | -1.80 | -1.80 |
| 643.83 | -0.16 | -0.16 |
| 530.67 | -0.77 | -0.77 |
| 433.56 | -0.68 | -0.68 |
| 1368.61 |