Basic Information
ID: ALA2187734
Type: Functional
Description: Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2187734
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 402.28 | 5.55 | 5.55 |
| 407.68 | 6.11 | 6.11 |
| 371.44 | 4.50 | 4.50 |
| 405.89 | 5.16 | 5.16 |
| 405.89 | 5.16 | 5.16 |
| 401.47 | 4.51 | 4.51 |
| 431.49 | 4.52 | 4.52 |
| 385.47 | 4.81 | 4.81 |
| 399.49 | 5.12 | 5.12 |
| 474.78 | 6.46 | 6.46 |
| 413.52 | 5.43 | 5.43 |
| 454.36 | 6.12 | 6.12 |
| 468.38 | 6.37 | 6.37 |
| 455.35 | 5.60 | 5.60 |
| 418.31 | 5.33 | 5.33 |
| 399.28 | 5.77 | 5.77 |
| 401.25 | 5.22 | 5.22 |
| 428.32 | 5.67 | 5.67 |
| 442.35 | 6.06 | 6.06 |
| 442.35 | 6.06 | 6.06 |
| 440.33 | 5.83 | 5.83 |
| 440.33 | 5.81 | 5.81 |
| 454.36 | 6.20 | 6.20 |
| 417.30 | 4.92 | 4.92 |
| 388.25 | 5.16 | 5.16 |
| 374.23 | 4.85 | 4.85 |
| 404.25 | 4.86 | 4.86 |
| 374.23 | 5.14 | 5.14 |
| 399.28 | 5.77 | 5.77 |
| 484.37 | 5.85 | 5.85 |
| 400.27 | 5.17 | 5.17 |
| 399.28 | 5.77 | 5.77 |
| 400.27 | 5.17 | 5.17 |
| 400.27 | 5.17 | 5.17 |
| 429.31 | 5.06 | 5.06 |
| 443.33 | 5.45 | 5.45 |
| 443.33 | 5.45 | 5.45 |
| 441.32 | 5.23 | 5.23 |
| 441.32 | 5.20 | 5.20 |
| 457.36 | 5.84 | 5.84 |