Inhibition of Plasmodium falciparum dihydrofolate dehydrogenase C276Y mutant expressed in Escherichia coli BL21(DE3) using dihydrofolate as substrate ...

Basic Information

ID: ALA2187986

Type: Binding

Description: Inhibition of Plasmodium falciparum dihydrofolate dehydrogenase C276Y mutant expressed in Escherichia coli BL21(DE3) using dihydrofolate as substrate at 100 uM by DCIP-based colorimetric analysis

Format: BAO_0000019

Organism: Plasmodium falciparum

Target:  Dihydroorotate dehydrogenase (quinone), mitochondrial(ALA3588732)

Document:  ALA2177061

Inhibition of Plasmodium falciparum dihydrofolate dehydrogenase C276Y mutant expressed in Escherichia coli BL21(DE3) using dihydrofolate as substrate at 100 uM by DCIP-based colorimetric analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
306.783.083.08
341.223.743.74
341.223.743.74
355.253.993.99