Basic Information
ID: ALA2188258
Type: Binding
Description: Inhibition of IDH1 R132H mutant expressed in human U87 cells assessed as inhibition of 2-hydroxyglutarate production after 48 hrs by LC/MS analysis
Organism: Homo sapiens
Cell type: U-87MG ATCC
Activity Charts
Bioactivity
Activity Types for Assay ALA2188258
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.57 | 4.86 | 4.86 |
| 512.63 | 6.02 | 6.02 |
| 497.61 | 6.31 | 6.31 |
| 464.61 | 5.96 | 5.96 |
| 465.59 | 5.36 | 5.36 |
| 459.57 | 5.30 | 5.30 |
| 497.61 | 6.38 | 6.38 |
| 450.58 | 5.57 | 5.57 |