Basic Information
ID: ALA2188262
Type: Binding
Description: Inhibition of IDH1 R132H mutant using alpha-ketoglutarate as substrate after 60 mins by resazurin-based fluorimetric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2188262
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 479.64 | 5.58 | 5.58 |
| 473.59 | 5.77 | 5.77 |
| 487.62 | 5.79 | 5.79 |
| 451.59 | 4.75 | 4.75 |
| 467.59 | 3.99 | 3.99 |
| 466.60 | 3.56 | 3.56 |
| 499.63 | 5.72 | 5.72 |
| 448.54 | 4.55 | 4.55 |
| 449.53 | 3.95 | 3.95 |
| 462.57 | 4.86 | 4.86 |
| 512.63 | 6.02 | 6.02 |
| 497.61 | 6.31 | 6.31 |
| 464.61 | 5.96 | 5.96 |
| 436.55 | 5.18 | 5.18 |
| 438.57 | 5.43 | 5.43 |
| 422.53 | 4.79 | 4.79 |
| 472.59 | 6.46 | 6.46 |
| 472.59 | 5.83 | 5.83 |
| 466.58 | 4.81 | 4.81 |
| 465.59 | 4.38 | 4.38 |
| 465.59 | 5.36 | 5.36 |
| 459.57 | 5.30 | 5.30 |
| 497.61 | 6.38 | 6.38 |
| 460.55 | 4.69 | 4.69 |
| 416.92 | 4.90 | 4.90 |
| 397.49 | 3.62 | 3.62 |
| 437.56 | 4.41 | 4.41 |
| 465.61 | 5.19 | 5.19 |
| 450.58 | 5.57 | 5.57 |
| 450.58 | 5.65 | 5.65 |
| 450.58 | 5.65 | 5.65 |
| 450.58 | 5.65 | 5.65 |
| 464.61 | 5.83 | 5.83 |
| 464.61 | 6.00 | 6.00 |
| 450.62 | 6.43 | 6.43 |
| 450.62 | 6.43 | 6.43 |