Basic Information
ID: ALA2188996
Type: Binding
Description: Inhibition of human recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting
Format: BAO_0000019
Organism: Homo sapiens
Target: Dual-specificity tyrosine-phosphorylation regulated kinase 1A(ALA2292)
Document: ALA2177089
Inhibition of human recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate and [gamma-33P]-ATP after 30 mins by scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2188996
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.47 | 5.07 | 5.07 |
| 338.37 | 3.11 | 3.11 |
| 338.37 | 3.11 | 3.11 |
| 326.36 | 3.31 | 3.31 |
| 388.43 | 4.67 | 4.67 |
| 378.46 | 4.62 | 4.62 |
| 372.43 | 4.56 | 4.56 |
| 388.43 | 4.27 | 4.27 |
| 388.43 | 4.27 | 4.27 |
| 401.26 | 4.17 | 4.17 |
| 401.26 | 4.17 | 4.17 |
| 401.26 | 4.17 | 4.17 |
| 340.36 | 3.55 | 3.55 |
| 358.35 | 3.68 | 3.68 |
| 460.15 | 6.02 | 6.02 |
| 352.39 | 3.42 | 3.42 |
| 405.50 | 4.40 | 4.40 |
| 327.43 | 3.82 | 3.82 |
| 321.38 | 4.01 | 4.01 |
| 322.37 | 3.41 | 3.41 |
| 323.36 | 2.80 | 2.80 |
| 323.36 | 2.80 | 2.80 |
| 323.36 | 2.80 | 2.80 |
| 328.40 | 3.47 | 3.47 |
| 342.42 | 3.78 | 3.78 |
| 405.48 | 4.53 | 4.53 |
| 311.35 | 2.73 | 2.73 |
| 325.37 | 2.74 | 2.74 |