Basic Information
ID: ALA2210067
Type: Functional
Description: Antagonist activity at RAGE transfected in CHO cells assessed as inhibition of amyloid beta 42-induced NFkappaB activation at 1 uM after 18 hrs by luciferase reporter gene assay
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA2210067
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 547.16 | 9.13 | 9.13 |
| 562.18 | 7.89 | 7.89 |
| 507.10 | 8.21 | 8.21 |
| 535.15 | 8.99 | 8.99 |
| 561.19 | 9.38 | 9.38 |
| 549.18 | 9.38 | 9.38 |
| 561.19 | 9.38 | 9.38 |
| 561.19 | 9.52 | 9.52 |
| 576.21 | 8.28 | 8.28 |
| 533.14 | 8.74 | 8.74 |