Basic Information
ID: ALA2210124
Type: Functional
Description: Antitumor activity against mixed-lineage human leukemia cells xenografted in NOD/SCID mouse assessed as reduction of CD45+CD33+ cells in bone marrow at 100 mg/kg, po qd administered every other day total of seven doses starting from 8 weeks post grafting measured on day 35 (Rvb = 9.8 %)
Organism: Homo sapiens
Tissue: Bone marrow
Cell type: Leukemia cell
Activity Charts
Bioactivity
Activity Types for Assay ALA2210124
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 409.48 | 2.38 | 2.38 |
| 329.87 | 1.98 | 1.98 |