Assay Report Card

Basic Information

ID: ALA2210125

Type: Functional

Description: Antitumor activity against human leukemia stem/progenitor cells xenografted in NOD/SCID mouse assessed as reduction of CD45+CD33+ cells in bone marrow at 100 mg/kg, po qd administered every other day total of seven doses starting from 8 weeks post grafting measured on day 85

Organism: Homo sapiens

Tissue: Bone marrow

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
409.482.382.38
329.871.981.98