Basic Information
ID: ALA2211411
Type: Binding
Description: Inhibition of APN in porcine kidney microsome assessed as inhibition of L-Leu-p-nitroanilide substrate hydrolysis incubated for 5 mins before substrate addition by UV-Vis spectrophotometric analysis
Organism: Sus scrofa
Tissue: Kidney
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2211411
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 308.38 | 0.53 | 0.53 |
| 315.37 | 2.88 | 2.88 |
| 341.41 | 3.40 | 3.40 |
| 295.34 | 1.74 | 1.74 |
| 283.30 | 1.87 | 1.87 |
| 279.34 | 2.04 | 2.04 |
| 285.37 | 1.47 | 1.47 |
| 309.37 | 1.41 | 1.41 |
| 309.37 | 1.41 | 1.41 |
| 297.33 | 1.54 | 1.54 |
| 309.37 | 1.41 | 1.41 |
| 293.37 | 1.71 | 1.71 |
| 297.33 | 1.54 | 1.54 |
| 313.36 | 2.04 | 2.04 |
| 329.36 | 1.74 | 1.74 |
| 303.29 | 2.19 | 2.19 |
| 285.30 | 2.05 | 2.05 |
| 329.40 | 2.56 | 2.56 |
| 308.38 | 2.27 | 2.27 |
| 264.32 | 1.27 | 1.27 |
| 307.39 | 1.84 | 1.84 |
| 317.32 | 1.87 | 1.87 |
| 325.43 | 1.55 | 1.55 |
| 327.38 | 2.17 | 2.17 |
| 321.42 | 2.23 | 2.23 |
| 321.42 | 2.23 | 2.23 |
| 355.44 | 2.43 | 2.43 |
| 341.41 | 2.56 | 2.56 |
| 299.33 | 1.73 | 1.73 |
| 313.36 | 1.77 | 1.77 |
| 265.31 | 1.73 | 1.73 |
| 269.30 | 1.00 | 1.00 |