Assay Report Card

Basic Information

ID: ALA2211909

Type: Binding

Description: Inhibition of human recombinant SIRT6 assessed as 7-amino-4-methylcoumarin labelled Arg-His-Lys-Lys(epsilon-acetyl) substrate deacetylation at 200 uM after 90 mins by Fluor-de-Lys assay

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
713.970.340.34
638.77-2.95-2.95
647.910.390.39
413.544.034.03
388.49-0.31-0.31
460.44
412.49-0.16-0.16
414.50-0.08-0.08
430.570.720.72
407.541.801.80
486.641.811.81
419.593.843.84