Basic Information
ID: ALA2212434
Type: Functional
Description: Positive allosteric modulation of human muscarinic M1 receptor expressing in CHONFAT cells assessed as potentiation of acetylcholine-induced calcium mobilization preincubated for 4 mins and measured 4 mins after acetylcholine stimulation by FLIPR assay
Organism: Homo sapiens
Cell type: CHONFAT
Activity Charts
Bioactivity
Activity Types for Assay ALA2212434
IP
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 309.32 | 2.76 | 2.76 |
| 388.43 | 2.45 | 2.45 |
| 515.68 | 4.16 | 4.16 |
| 499.62 | 3.44 | 3.44 |
| 485.59 | 2.79 | 2.79 |
| 485.59 | 2.79 | 2.79 |
| 499.62 | 3.18 | 3.18 |
| 499.62 | 3.18 | 3.18 |
| 484.60 | 3.39 | 3.39 |
| 485.59 | 2.53 | 2.53 |
| 475.59 | 2.36 | 2.36 |
| 511.63 | 3.20 | 3.20 |
| 518.64 | 2.66 | 2.66 |
| 390.48 | 4.12 | 4.12 |
| 398.46 | 4.62 | 4.62 |
| 387.44 | 1.85 | 1.85 |
| 401.47 | 2.11 | 2.11 |
| 441.54 | 2.99 | 2.99 |
| 477.57 | 4.31 | 4.31 |
| 503.61 | 4.34 | 4.34 |
| 517.63 | 4.65 | 4.65 |
| 468.52 | 2.13 | 2.13 |
| 464.53 | 3.40 | 3.40 |
| 427.51 | 2.64 | 2.64 |
| 441.54 | 3.03 | 3.03 |
| 455.56 | 3.42 | 3.42 |
| 469.59 | 3.81 | 3.81 |
| 483.62 | 4.20 | 4.20 |
| 471.56 | 2.66 | 2.66 |
| 471.56 | 2.66 | 2.66 |
| 485.59 | 3.00 | 3.00 |
| 487.63 | 3.38 | 3.38 |
| 483.62 | 4.06 | 4.06 |
| 505.57 | 4.06 | 4.06 |
| 487.58 | 3.76 | 3.76 |