Basic Information
ID: ALA2213246
Type: Binding
Description: Inhibition of cathepsin S using FR-aminoluciferin as substrate preincubated for 15 mins before substrate addition measured after 1 hr by luminescence assay
Activity Charts
Bioactivity
Activity Types for Assay ALA2213246
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 399.56 | 4.82 | 4.82 |
| 407.39 | 1.60 | 1.60 |
| 447.45 | 2.38 | 2.38 |
| 405.54 | 1.47 | 1.47 |
| 392.46 | 2.44 | 2.44 |
| 358.45 | 1.95 | 1.95 |
| 355.51 | 3.94 | 3.94 |
| 349.48 | 3.88 | 3.88 |
| 341.48 | 3.76 | 3.76 |
| 335.45 | 3.70 | 3.70 |
| 355.47 | 3.40 | 3.40 |
| 367.43 | 3.48 | 3.48 |
| 379.46 | 3.35 | 3.35 |
| 339.40 | 2.94 | 2.94 |
| 383.88 | 4.00 | 4.00 |
| 369.49 | 3.71 | 3.71 |
| 356.45 | 2.80 | 2.80 |
| 350.43 | 2.74 | 2.74 |
| 406.49 | 2.70 | 2.70 |
| 356.45 | 2.80 | 2.80 |
| 367.43 | 3.48 | 3.48 |
| 353.43 | 2.08 | 2.08 |
| 339.40 | 2.07 | 2.07 |
| 356.45 | 2.80 | 2.80 |
| 340.39 | 2.33 | 2.33 |
| 389.46 | 4.09 | 4.09 |
| 427.53 | 2.75 | 2.75 |
| 340.39 | 2.33 | 2.33 |
| 363.46 | 3.65 | 3.65 |
| 356.47 | 3.11 | 3.11 |
| 340.39 | 2.33 | 2.33 |
| 340.39 | 2.33 | 2.33 |
| 442.55 | 2.25 | 2.25 |
| 363.46 | 3.65 | 3.65 |
| 389.46 | 2.99 | 2.99 |
| 395.49 | 3.05 | 3.05 |
| 407.48 | 2.10 | 2.10 |
| 357.46 | 2.45 | 2.45 |
| 366.43 | 2.03 | 2.03 |
| 428.52 | 1.99 | 1.99 |
| 341.46 | 3.22 | 3.22 |
| 417.44 | 4.36 | 4.36 |
| 340.39 | 2.33 | 2.33 |
| 398.51 | 2.29 | 2.29 |
| 406.51 | 1.35 | 1.35 |
| 407.56 | 1.72 | 1.72 |
| 348.45 | 1.54 | 1.54 |
| 413.59 | 5.07 | 5.07 |
| 413.59 | 5.07 | 5.07 |
| 371.51 | 3.90 | 3.90 |
| 371.51 | 3.90 | 3.90 |
| 357.48 | 3.33 | 3.33 |
| 385.54 | 4.07 | 4.07 |
| 383.52 | 3.82 | 3.82 |
| 369.49 | 3.58 | 3.58 |
| 355.47 | 3.40 | 3.40 |
| 357.48 | 3.65 | 3.65 |
| 343.46 | 3.48 | 3.48 |
| 341.44 | 3.01 | 3.01 |
| 315.40 | 2.48 | 2.48 |
| 391.45 | 3.65 | 3.65 |
| 369.49 | 3.79 | 3.79 |
| 349.42 | 2.87 | 2.87 |
| 383.86 | 3.53 | 3.53 |
| 377.47 | 3.46 | 3.46 |
| 357.44 | 2.39 | 2.39 |
| 357.44 | 2.25 | 2.25 |
| 357.44 | 2.25 | 2.25 |
| 405.51 | 1.65 | 1.65 |
| 365.44 | 0.87 | 0.87 |
| 379.47 | 1.26 | 1.26 |
| 339.40 | 2.94 | 2.94 |
| 340.39 | 2.33 | 2.33 |
| 431.57 | 5.07 | 5.07 |
| 349.44 | 3.34 | 3.34 |
| 350.43 | 2.74 | 2.74 |
| 374.45 | 3.21 | 3.21 |
| 432.53 | 3.69 | 3.69 |
| 406.49 | 3.30 | 3.30 |
| 442.55 | 2.71 | 2.71 |