Basic Information
ID: ALA2213859
Type: Functional
Description: Antagonist activity at human NPBWR1 expressed in HEK293T cells co-expressing Galphaqi3 assessed as calcium release after 15 mins by FLIPR assay assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK-293T
Target: Neuropeptides B/W receptor type 1(ALA1293293)
Document: ALA2202992
Antagonist activity at human NPBWR1 expressed in HEK293T cells co-expressing Galphaqi3 assessed as calcium release after 15 mins by FLIPR assay assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2213859
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 346.75 | 3.83 | 3.83 |
| 328.76 | 3.69 | 3.69 |
| 342.78 | 4.00 | 4.00 |
| 364.40 | 3.97 | 3.97 |
| 380.75 | 5.01 | 5.01 |
| 363.20 | 4.34 | 4.34 |
| 358.78 | 3.70 | 3.70 |
| 396.75 | 4.89 | 4.89 |
| 372.81 | 4.00 | 4.00 |
| 340.81 | 4.55 | 4.55 |
| 368.82 | 4.56 | 4.56 |
| 382.85 | 4.57 | 4.57 |
| 382.85 | 4.57 | 4.57 |
| 356.81 | 4.39 | 4.39 |
| 384.86 | 4.98 | 4.98 |
| 362.43 | 4.80 | 4.80 |
| 370.84 | 4.81 | 4.81 |
| 370.84 | 4.29 | 4.29 |
| 361.40 | 4.03 | 4.03 |
| 384.86 | 5.12 | 5.12 |
| 312.76 | 3.99 | 3.99 |
| 366.42 | 3.65 | 3.65 |
| 384.44 | 5.01 | 5.01 |
| 424.81 | 5.70 | 5.70 |
| 350.42 | 4.47 | 4.47 |
| 384.86 | 5.20 | 5.20 |
| 356.81 | 4.30 | 4.30 |
| 370.84 | 4.81 | 4.81 |
| 429.31 | 5.31 | 5.31 |
| 378.82 | 4.84 | 4.84 |
| 374.40 | 4.60 | 4.60 |
| 356.81 | 4.30 | 4.30 |
| 364.45 | 4.72 | 4.72 |
| 348.40 | 4.22 | 4.22 |
| 342.78 | 4.00 | 4.00 |
| 356.81 | 4.30 | 4.30 |
| 342.78 | 3.48 | 3.48 |
| 400.82 | 3.86 | 3.86 |
| 394.43 | 3.94 | 3.94 |
| 356.81 | 4.25 | 4.25 |
| 415.29 | 4.92 | 4.92 |
| 414.85 | 4.51 | 4.51 |
| 428.87 | 4.60 | 4.60 |
| 442.90 | 4.99 | 4.99 |
| 336.39 | 4.16 | 4.16 |
| 351.41 | 3.74 | 3.74 |
| 393.44 | 4.12 | 4.12 |
| 372.81 | 4.00 | 4.00 |
| 378.82 | 4.84 | 4.84 |
| 328.76 | 3.69 | 3.69 |
| 356.81 | 4.51 | 4.51 |
| 397.86 | 3.94 | 3.94 |
| 370.84 | 4.69 | 4.69 |
| 356.81 | 3.79 | 3.79 |
| 387.23 | 4.10 | 4.10 |
| 380.40 | 3.86 | 3.86 |
| 396.75 | 4.71 | 4.71 |
| 386.84 | 4.47 | 4.47 |
| 407.65 | 4.45 | 4.45 |
| 363.20 | 4.34 | 4.34 |
| 398.89 | 5.42 | 5.42 |
| 404.85 | 5.35 | 5.35 |
| 356.81 | 4.30 | 4.30 |
| 356.81 | 4.30 | 4.30 |
| 407.65 | 4.45 | 4.45 |
| 356.81 | 4.25 | 4.25 |