Basic Information
ID: ALA2214941
Type: ADME
Description: Ratio of permeability from apical to basal side of MDCK2 cells expressing MDR1 assessed as fraction of mass extracted by methanol wash at 5 uM in presence of LSN 335984 to permeability from apical to basal side of MDCK2 cells expressing MDR1 assessed as fraction of mass extracted by methanol wash at 5 uM in absence of LSN 335984
Organism: Canis lupus familiaris
Cell type: MDCK-II
Activity Charts
Bioactivity
Activity Types for Assay ALA2214941
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 637.72 | 5.99 | 5.99 |
| 689.80 | 6.63 | 6.63 |
| 609.64 | 5.31 | 5.31 |
| 625.71 | 5.85 | 5.85 |
| 621.65 | 5.46 | 5.46 |
| 661.72 | 5.95 | 5.95 |
| 677.79 | 6.48 | 6.48 |
| 673.73 | 6.09 | 6.09 |
| 663.73 | 6.37 | 6.37 |
| 679.80 | 6.90 | 6.90 |
| 675.74 | 6.51 | 6.51 |
| 691.81 | 7.05 | 7.05 |