Basic Information
ID: ALA2214945
Type: ADME
Description: Ratio of permeability from basal to apical side of MDCK2 cells expressing MDR1 in absence of LSN 335984 to permeability from basal to apical side of MDCK2 cells expressing MDR1 in presence of LSN 335984
Format: BAO_0000219
Organism: Canis lupus familiaris
Cell type: MDCK-II
Target: ADMET(ALA612558)
Document: ALA2203082
Ratio of permeability from basal to apical side of MDCK2 cells expressing MDR1 in absence of LSN 335984 to permeability from basal to apical side of MDCK2 cells expressing MDR1 in presence of LSN 335984: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2214945
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 637.72 | 5.99 | 5.99 |
| 689.80 | 6.63 | 6.63 |
| 609.64 | 5.31 | 5.31 |
| 625.71 | 5.85 | 5.85 |
| 621.65 | 5.46 | 5.46 |
| 661.72 | 5.95 | 5.95 |
| 677.79 | 6.48 | 6.48 |
| 673.73 | 6.09 | 6.09 |
| 663.73 | 6.37 | 6.37 |
| 679.80 | 6.90 | 6.90 |
| 675.74 | 6.51 | 6.51 |
| 691.81 | 7.05 | 7.05 |