Basic Information
ID: ALA2214953
Type: Binding
Description: Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake at 5*10'-6 M incubated for 30 mins prior to calcein AM influx measured after 20 mins by fluorimetric analysis relative to LSN 335984
Cell type: MDCK-II
Activity Charts
Bioactivity
Activity Types for Assay ALA2214953
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 637.72 | 5.99 | 5.99 |
| 689.80 | 6.63 | 6.63 |
| 609.64 | 5.31 | 5.31 |
| 625.71 | 5.85 | 5.85 |
| 621.65 | 5.46 | 5.46 |
| 661.72 | 5.95 | 5.95 |
| 677.79 | 6.48 | 6.48 |
| 673.73 | 6.09 | 6.09 |
| 663.73 | 6.37 | 6.37 |
| 679.80 | 6.90 | 6.90 |
| 675.74 | 6.51 | 6.51 |
| 691.81 | 7.05 | 7.05 |