Basic Information
ID: ALA2214988
Type: Binding
Description: Inhibition of P-gp-mediated paclitaxel resistance in human LCC6MDR cells assessed as fold decrease in paclitaxel IC50 for cytotoxic activity at 0.5 uM after 5 days by MTS assay relative to parental cells
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2214988
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.61 | 5.09 | 5.09 |
| 1202.63 | ||
| 634.68 | 6.74 | 6.74 |
| 1214.65 | ||
| 677.75 | 6.02 | 6.02 |
| 733.81 | 6.98 | 6.98 |
| 733.81 | 7.96 | 7.96 |
| 723.82 | 8.23 | 8.23 |
| 768.82 | 8.13 | 8.13 |
| 781.86 | 8.01 | 8.01 |
| 724.81 | 7.62 | 7.62 |
| 724.81 | 7.62 | 7.62 |
| 733.77 | 6.42 | 6.42 |
| 711.79 | 5.99 | 5.99 |
| 787.89 | 7.72 | 7.72 |
| 751.88 | 8.66 | 8.66 |
| 741.81 | 8.37 | 8.37 |
| 741.81 | 8.37 | 8.37 |
| 741.81 | 8.37 | 8.37 |
| 777.79 | 8.64 | 8.64 |
| 791.82 | 9.25 | 9.25 |
| 633.70 | 6.31 | 6.31 |
| 661.75 | 7.05 | 7.05 |
| 866.99 | 8.63 | 8.63 |
| 759.80 | 8.50 | 8.50 |
| 661.75 | 6.93 | 6.93 |
| 693.75 | 6.33 | 6.33 |
| 845.95 | 9.47 | 9.47 |
| 669.68 | 6.59 | 6.59 |
| 806.87 | 7.32 | 7.32 |
| 731.84 | 7.99 | 7.99 |
| 737.81 | 7.87 | 7.87 |
| 704.78 | 5.90 | 5.90 |
| 793.87 | 7.98 | 7.98 |
| 761.87 | 8.58 | 8.58 |
| 793.87 | 7.98 | 7.98 |
| 946.06 | 11.12 | 11.12 |
| 769.79 | 8.24 | 8.24 |
| 693.75 | 6.33 | 6.33 |